Chemdle

Chemdle is a daily chemistry puzzle where your mission is to solve a curated problem in 6 attempts or fewer. Expect questions on everything from named reactions to total synthesis.

Each day presents a new chemistry challenge drawn from organic, physical, or computational chemistry. You'll work through molecular structures, reaction mechanisms, or synthetic pathways, guessing the answer step by step. Wrong guesses narrow the field, and hints are available if you get stuck.

• You have 6 guesses to solve the problem.
• Problems range from mechanism identification to multi-step synthesis.
• Hints unlock if you need a nudge in the right direction.
• A new puzzle drops every day, covering all corners of chemistry.
• Community-submitted puzzles keep the game fresh and challenging.

Why we like it:

• ✅Built by chemists for chemists, so the problems are thoughtful and accurate.
• ✅Difficulty spans from undergraduate review to research-level challenges.
• ✅Even a wrong answer sharpens your mechanistic thinking for next time.

Hint: Start broad. Identify reaction type, key functional groups, or stereochemistry before committing to a specific reagent or mechanism. The first guess sets the tone for the rest.